Opening Pandora's box: clinical data and the study of complex diseases.

Research paper by Michael N MN Liebman

Indexed on: 02 May '02Published on: 02 May '02Published in: Science's STKE : signal transduction knowledge environment


Complex diseases have complex phenotypes, and proper diagnosis requires that the analysis take into account the patient's history and exposure to environmental factors, as well as genetic information. Signaling information is one aspect of a grander "biomedical informatics" approach advocated for a better understanding of a patient's medically relevant disease phenotype.