Number of Preoperative Abdominal False Lumen-Perfused Small Branches Is Related to Abdominal Aortic Remodeling after Thoracic Endovascular Aortic Repair for Type B Aortic Dissection.

Research paper by Yangyang Y Ge, Xiaomeng X Lv, Xiaohu X Ge, Jianhang J Miu, Weidong W Fan, Dan D Rong, Wei W Guo

Indexed on: 20 Sep '20Published on: 20 Sep '20Published in: Annals of Vascular Surgery


Abdominal aortic enlargement (AAE) is a commonly seen complication after thoracic endovascular aortic repair (TEVAR) for type B aortic dissection (TBAD). This study assessed the relationship between preoperative abdominal false lumen-perfused small branches (pre-AFLSB) and risk of AAE after TEVAR for TBAD extending through abdominal aorta. One hundred and eighty-four patients with TBAD who had been treated by TEVAR at four hospitals in China were stratified according to median pre-AFLSB: ≤8 (Group A) and >8 (Group B). AAE was defined as ≥20% increase in abdominal total aortic volume, measured using imaging software featuring centerline analysis, on most recent postoperative computed tomography angiography relative to preoperative examination. Multivariable Cox proportional hazard regression was used to evaluate the relationship between the number of pre-AFLSB and the risk of AAE after TEVAR. At median 12.4 months imaging follow-up, AAE was present in 65 patients at higher cumulative rate (log-rank test P<.001) in Group B, which had more frequent partially thrombosed or patent abdominal false lumen than Group A at 6-12 months (P<.01) and 12-24 months (P=.03) of follow-up. In a multivariable Cox proportional hazard regression model, the number of pre-AFLSB was independently associated with risk of AAE after TEVAR (hazard ratio [for one increase], 1.10; 95% confidence interval, 1.00-1.21; P=.04) after adjustment for age, gender, dissection chronicity, SVS risk score, preoperative maximum descending aortic diameter, false lumen status of abdominal aorta, numbers of false lumen-perfused visceral arteries, abdominal intimal larger tears, and preoperative abdominal intimal small tears, and dissection length and descending aortic length ratio. The number of pre-AFLSB was positively associated with the risk of AAE after TEVAR for TBAD extending through the abdominal aorta. Copyright © 2020. Published by Elsevier Inc.