Non-progressive cerebellar ataxia and previous undetermined acute cerebellar injury: a mysterious clinical condition.

Research paper by Wladimir Bocca Vieira de Rezende WB Pinto, José Luiz JL Pedroso, Paulo Victor Sgobbi de PV Souza, Marcus Vinícius Cristino de MV Albuquerque, Orlando Graziani Povoas OG Barsottini

Indexed on: 21 Aug '15Published on: 21 Aug '15Published in: Arquivos de neuro-psiquiatria


Cerebellar ataxias represent a wide group of neurological diseases secondary to dysfunctions of cerebellum or its associated pathways, rarely coursing with acute-onset acquired etiologies and chronic non-progressive presentation. We evaluated patients with acquired non-progressive cerebellar ataxia that presented previous acute or subacute onset. Clinical and neuroimaging characterization of adult patients with acquired non-progressive ataxia were performed. Five patients were identified with the phenotype of acquired non-progressive ataxia. Most patients presented with a juvenile to adult-onset acute to subacute appendicular and truncal cerebellar ataxia with mild to moderate cerebellar or olivopontocerebellar atrophy. Establishing the etiology of the acute triggering events of such ataxias is complex. Non-progressive ataxia in adults must be distinguished from hereditary ataxias.