Nipping fear in the bud: inhibitory control in the amygdala.

Research paper by Vadim Y VY Bolshakov

Indexed on: 28 Mar '09Published on: 28 Mar '09Published in: Neuron


Cortical and thalamic inputs to the lateral amygdala are recruited during auditory fear conditioning. In this issue of Neuron, Pan et al. describe a new mechanism of GABA-mediated modulation at these synapses, involving target-specific suppression of glutamate release through differential activation of GABAb receptors on glutamatergic inputs to neurons and interneurons.