Indexed on: 01 Feb '93Published on: 01 Feb '93Published in: Folia Microbiologica
Netropsin suppressed the increase of intracellular proteolytic activity when added toB. megaterium incubated in a sporulation medium. The inhibited enzyme was a Ca2+-dependent serine proteinase. Sporulation and protein turnover in later sporulation phases were inhibited as well. Different concentrations of netropsin affected various aspects of protein catabolism differently.