N-Iodosuccinimide involved one-pot metal-free synthesis of 2-heteroaromatic benzothiazole compounds.

Research paper by Xianglong X Chu, Tiantian T Duan, Xuan X Liu, Lei L Feng, Jiong J Jia, Chen C Ma

Indexed on: 25 Jan '17Published on: 25 Jan '17Published in: Organic & Biomolecular Chemistry


A one-pot protocol for the synthesis of structurally diverse 2-hetarylbenzothiazoles via oxidative condensation of the sp(3) C-H bond with benzothiazoles has been described. This process is metal free and operationally simple. A series of 2-hetarylbenzothiazoles were prepared in moderate to good yield under mild conditions.