Medical and Surgical Illnesses During Pregnancy: Perspectives on Immediate and Long-term Outcomes

Research paper by Vesna D. Garovic, Andrea Kattah, Carl H. Rose, Katherine W. Arendt

Indexed on: 12 Sep '16Published on: 01 Sep '16Published in: Mayo Clinic Proceedings


Pregnancy is a physiologic state characterized by dynamic vascular and metabolic changes that are required for adequate uteroplacental circulation and for fetal growth and development. Pregnancy is also commonly viewed as a “physiologic stress test,” whereby maternal physiologic changes may expose or unmask underlying previously silent cardiovascular and metabolic abnormalities. A “failed stress test”—eg, manifesting either as hypertensive disorders in pregnancy (HDP), gestational diabetes mellitus (GDM), or both—has both short- and long-term implications for maternal cardiovascular and metabolic health.