Lymphomatoid Papulosis and Other Lymphoma-Like Diseases.

Research paper by Adrian A Moy, James J Sun, Sophia S Ma, Lucia L Seminario-Vidal

Indexed on: 11 Oct '20Published on: 31 Aug '19Published in: Dermatologic Clinics


Pityriasis lichenoides et varioliformis acuta and pityriasis lichenoides chronica are the 2 main subtypes of pityriasis lichenoides. They represent the acute and chronic forms of the disease; both may have clonal T cells. Several treatment modalities are used, but it has been difficult to determine efficacy because of the possibility of spontaneous remission. Cutaneous CD30+ lymphoproliferative disorders constitute many cutaneous T-cell lymphomas and comprise lymphomatoid papulosis and primary cutaneous anaplastic large cell lymphoma (ALCL). Both have an excellent prognosis. Lymphomatoid papulosis often only requires observation or treatment of symptoms. First-line therapies for primary cutaneous ALCL are surgical excision or radiotherapy. Copyright © 2019 Elsevier Inc. All rights reserved.