Intravascular large B-cell lymphoma of the cutaneous variant in Korea.

Research paper by Ji-Hye JH Park, Dong-Youn DY Lee, Young-Hye YH Ko

Indexed on: 29 Jan '11Published on: 29 Jan '11Published in: The Journal of Dermatology


Intravascular large B-cell lymphoma (IVLBCL) is a rare subtype of diffuse large B-cell lymphoma. It is characterized by proliferation of malignant lymphoid cells within the small vessels of various organs. The skin and central nervous system are commonly involved although it occurs in other organs such as the kidneys, adrenals, lung and liver. In Western patients, there is a cutaneous variant of IVLBCL, which involves only the skin. However, the Asian variant, which rarely involves the skin, is associated with hemophagocytosis. It was reported in the majority of Japanese patients. Here, we report a case of the cutaneous variant of IVLBCL in a Korean individual.