In vitro regulation of cell behavior by calcium phosphates synthesized by the mechanochemical method

Research paper by A. V. Karlov, I. A. Khlusov, N. S. Pozhen’ko, M. V. Chaikina

Indexed on: 01 Sep '04Published on: 01 Sep '04Published in: Bulletin of Experimental Biology and Medicine


Biological activity of eight hydroxyapatite powders synthesized by the mechanochemical method was studiedin vitro. Introduction of copper and zinc atoms into synthetic hydroxy-apatite structure promotes cell adhesion. Hydroxyapatites obtained by the mechanochemical method are promising base for a new class of materials and coatings with regulated bioactivity for orthopedics and traumatology.