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Heterocyclic analogs of corticosteroids

Research paper by A. A. Akhrem, L. I. Ukhova, N. F. Uskova, N. F. Marchenko

Indexed on: 01 Dec '68Published on: 01 Dec '68Published in: Russian Chemical Bulletin



Abstract

In the oxidation of the acetates of the isomeric decahydro-1,2-dimethyl-4-vinyl-4-quinolinols with one molecular proportion of peracetic acid decahydro-1,2-dimethyl-4-vinyl-4-quinolinol 1-oxides are formed.In the oxidation of the isomeric decahydro-1,2-dimethyl-4-vinyl-4-quinolinols with performic acid the corresponding 4-(epoxyethyl)decahydro-1,2-dimethyl-4-quinolinols are formed.In acid hydrolysis 4-(epoxyethyl)decahydro-1,2-dimethyl-4-quinolinols form the corresponding 4-(1,2-dihydroxyethyl)decahydro-1,2-dimethyl-4-quinolinols.