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Hepatitis B virus infection among household contacts of patients with acute HBsAg-positive hepatitis

Research paper by the Copenhagen Hepatitis Acuta Programme, J. Aldershvile, F. Hardt, J. O. Nielsen, M. Orholm, U. Tage-Jensen

Indexed on: 01 Jul '81Published on: 01 Jul '81Published in: Infection



Abstract

Sixty-seven household contacts of 31 index cases with acute HBsAg-positive hepatitis were investigated forHepatitis B virus (HBV) markers. Follow-up findings in 50 household contacts revealed that six spouses and/or sexual partners had developed acute clinical hepatitis B. Three of these six contacts were drug addicts. A further seven contacts showed serological changes compatible with exposure to HBV, but had no signs of acute clinical hepatitis. Six of these seven contacts were spouses and/or sexual partners of their index case. Possible prophylactic or post-exposure measures only seem to be necessary in the spouses and/or sexual partners of patients with acute hepatitis B.