Hepatic radiation injury mimicking metastasis in distal esophageal cancer().

Research paper by Karel K Demey, Hans H Van Veer, Philippe P Nafteux, Christophe M CM Deroose, Karin K Haustermans, Johan J Coolen, Vincent V Vandecaveye, Willy W Coosemans, Eric E Van Cutsem

Indexed on: 28 Oct '16Published on: 28 Oct '16Published in: Acta chirurgica Belgica


A new hypermetabolic lesion on (18)FDG-PET/CT after neo-adjuvant chemoradiotherapy for distal esophageal cancer can be a hepatic metastasis and should be examined carefully before esophagectomy.We present a case of acute and nodular radiation-induced injury of the left liver after neo-adjuvant chemoradiotherapy for distal esophageal cancer, which resembles a hepatic metastasis on (18)FDG-PET/CT. Acute and nodular radiation hepatitis (RH) can be a potential cause of false-positive findings of malignancy and therefore exclude patients who could benefit from esophagectomy.(18)FDG-PET/CT images should therefore carefully be interpreted and compared with the radiation beams, dose distribution and eventually clarified by DW-MR imaging.