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Hemophagocytic lymphohistiocytosis in the setting of HELLP Syndrome.

Research paper by Sarmen S Sarkissian, Yasir Y Khan, Daniel D Farrell, David D Constable, Elizabeth E Brem

Indexed on: 20 Dec '18Published on: 20 Dec '18Published in: Clinical Case Reports



Abstract

Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening hyper activation of the immune system. Rare cases associated with HELLP syndrome and other similar conditions in pregnancy have been reported. Despite the improved survival rates with etoposide and dexamethasone-based regimens, HLH remains a challenging disease. Experience in pregnant patients is exceedingly rare.