Glaucogenin E, a new C21 steroid from Cynanchum stauntonii.

Research paper by Mi M Zhang, Jun-Song JS Wang, Jun J Luo, Dan-Dan DD Wei, Ling-Yi LY Kong

Indexed on: 06 Apr '12Published on: 06 Apr '12Published in: Natural product research


Glaucogenin E (1), a new C(21) steroid sapogenin, along with three known ones (2-4) were isolated from the rhizomes of Cynanchum stauntonii (Decne.) Schltr. ex Levl. Their structures were established mainly by the spectroscopic analysis, including 2D NMR. All the isolated compounds were evaluated for their cytotoxicity against human cancer cell lines HeLa, Bel-7402, SGC-7901 and BGC-823.