Genetic analysis of 15 STR loci in Chinese Han population from West China.

Research paper by Ya-Jun YJ Deng, Jiang-Wei JW Yan, Xiao-Guang XG Yu, Yuan-Zhe YZ Li, Hao-Fang HF Mu, Yan-Qing YQ Huang, Xiao-Tie XT Shi, Wei-Min WM Sun

Indexed on: 19 Jun '07Published on: 19 Jun '07Published in: Genomics, Proteomics & Bioinformatics


Allele frequencies for 15 short tandem repeat (STR) loci (D8S1179, D21S11, D7S820, CSF1PO, D3S1358, TH01, D13S317, D16S539, D2S1338, D19S433, vWA, TPOX, D18S51, D5S818, and FGA) were obtained from 7,636 unrelated individuals of Chinese Han population living in Qinghai and Chongqing, China. Totally 206 alleles were observed, with the corresponding allele frequencies ranging from 0.0001-0.4982. Chi-square test showed that all of the STR loci agreed with the Hardy-Weinberg equilibrium. We also compared our data with previously published population data of other ethnics or areas. The results are valuable for human identification and paternity testing in Chinese Han population.