Gastrointestinal cancer: Neutrophils and cancer: guilt by association

Research paper by Craig N. Jenne, Paul Kubes

Indexed on: 05 Jun '16Published on: 02 Jun '16Published in: Nature Reviews Gastroenterology and Hepatology


A new study reports that activation of neutrophils leads to the release of neutrophil extracellular traps (NETs) and coagulation, which then promote development of a tumorigenic microenvironment in the small intestine. These findings provide novel insights into the role of neutrophils in cancer and suggest enticing directions for future research.