Four hundred fifty-three consecutive pancreaticoduodenectomies with pancreaticogastrostomy.

Research paper by Emanuel E Eguia, Eileen A EA O'Halloran, Marc A MA Borge, Kenneth K Micetich, Gerard V GV Aranha

Indexed on: 20 Dec '18Published on: 20 Dec '18Published in: The American Journal of Surgery®


Patients who undergo pancreaticoduodenectomy (PD) have the pancreatic remnant (PR) anastomosed to the jejunum. In this study, all patients had the PR anastomosed to the stomach. Our aims are to evaluate postoperative outcomes of patients undergoing PD with pancreaticogastrostomy (PG). There was 453 patients who underwent PD with PG. Preoperative characteristics, intraoperative data, and postoperative outcomes were analyzed using univariate and multivariate models. The patient cohort had a median age of 67 years and underwent resection for pancreatic (40.8%), ampullary (15.9%), duodenal (6.6%), distal bile duct (6.4%) cancers. Multivariate analysis revealed poor prognosis was related to age, tumor diameter, lymph node ratio, perineural invasion, and tumor differentiation in patients with periampullary adenocarcinoma. This series of patients undergoing PD with PG shows that the operation can be performed safely with excellent outcomes for a variety of malignant and benign conditions. Copyright © 2018 Elsevier Inc. All rights reserved.