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First osmium-catalysed ketamination of alkenes.

Research paper by Amparo A Villar, Claas H CH Hövelmann, Martin M Nieger, Kilian K Muñiz

Indexed on: 29 Jun '05Published on: 29 Jun '05Published in: Chemical Communications



Abstract

Conditions for a first oxidative conversion of alkenes into 2-amino ketones are described, which yield racemic products within a direct oxidation pathway and 2-amino ketones with up to 99% enantiomeric excess from the corresponding enantiopure amino alcohols.