Fecal transplantation as a treatment for Clostridium difficile infection in patients with ulcerative colitis.

Research paper by Marta M Izquierdo Romero, Pilar P Varela Trastoy, Alejo A Mancebo Mata

Indexed on: 28 Jul '17Published on: 28 Jul '17Published in: Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva


Clostridium difficile (CD) infection is currently the most frequent etiology of nosocomial diarrhea. Besides, its incidence is progressively increasing in ambulatory patients. Inflammatory bowel disease (IBD) is a risk factor of CD infection itself, but also due to the regular immunosuppressive treatment used in these patients. At the present time, fecal transplantation (FT) is a safe and cost-effective alternative if the previous antibiotic treatments have failed. Similar outcomes between patients with IBD and general population have been reported. We present a case of a patient with ulcerative colitis and recurrent CD infection successfully treated with FT.