Evidence-based review of the nonsurgical management of hyperhidrosis.

Research paper by Rafael R Reisfeld, Karen I KI Berliner

Indexed on: 19 Jun '08Published on: 19 Jun '08Published in: Thoracic Surgery Clinics


The most common nonsurgical modern treatments for hyperhidrosis include topical treatments such as aluminum chloride, iontophoresis (usually with tap water), oral medications such as anticholinergics, and BTX-A. Topical treatments should always be first-line therapy. For those who fail such treatment, iontophoresis is typically recommended for those with palmar or plantar hyperhidrosis, whereas BTX is often considered as first- or second-line therapy in severe axillary hyperhidrosis. Oral anticholinergics are considered after failure of all other nonsurgical treatments.