Ethyl 4-hydroxy-methyl-2-methyl-pyridine-5-carboxyl-ate.

Research paper by Peter D W PD Boyd, Gersande G Lena, Julie A JA Spicer

Indexed on: 01 Jan '08Published on: 01 Jan '08Published in: Acta Crystallographica Section E


The title compound, C(10)H(13)NO(3), was obtained as a by-product of the aldolization reaction of furo[3,4-c]pyridin-3(1H)-one with thio-phene-2-carboxaldehyde. The substituents on the pyridine ring are nearly coplanar, with an 8.1 (2)° rotation of the hydroxmethyl group from this plane. The mol-ecules assemble in the crystal structure as chains via O-H⋯N hydrogen bonding between the pyridine N atom and a neighbouring hydroxy-methyl OH group.