Enhanced Biomimic Bactericidal Surfaces by Coating with Positively-Charged ZIF Nano-Dagger Arrays.

Research paper by Yuan Y Yuan, Yugen Y Zhang

Indexed on: 15 Jun '17Published on: 15 Jun '17Published in: Nanomedicine: Nanotechnology, Biology and Medicine


Cicada wing surfaces are covered with dense patterns of nano-pillar structure that prevent bacterial growth by rupturing adhered microbial cells. To mimic the natural nano-pillar structure, we developed a general and simple method to grow metal organic framework (MOF) nano-dagger arrays on a wide range of surfaces. These nano-daggers possess high bactericidal activity, with log reduction >7 for Escherichia coli and Staphylococcus aureus. It was hypothesized that the positively-charged ZIF-L nano-dagger surfaces enhance bacterial cell adhesion, facilitating selective and efficient bacteria killing by the rigid and sharp nano-dagger tips. This research provides a safe and clean antimicrobial surface technology which does not require external chemicals and will not cause drug resistance.