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Emerging therapies for the treatment of neovascular age related macular degeneration.

Research paper by Alex A Yuan, Peter K PK Kaiser

Indexed on: 26 May '11Published on: 26 May '11Published in: Seminars in ophthalmology



Abstract

Numerous drugs that show promise in the treatment of neovascular age related macular degeneration are currently being evaluated in early clinical trials. Some of these drugs target the vascular endothelial growth factor pathway while others act on different targets along the angiogenesis cascade. The mechanism of action of these novel therapeutics and the results of early clinical trials will be discussed along with a review of angiogenesis.