Effects of serotonin and ketanserin on the functional morphology of chick down feather bulbi in vitro

Research paper by H. Beele, H. Thierens, B. Verhasselt, L. de Ridder

Indexed on: 01 Oct '90Published on: 01 Oct '90Published in: Cellular and Molecular Life Sciences


Chick feather bulbi cultured in vitro showed an increased DNA synthesis and a delayed keratinization after treatment with ketanserin, a serotonin2 antagonist with wound-healing properties. In contrast, serotonin stimulates keratinization of the keratinocytes in the bulbus.