Effect of Varying Viscosity on Two-Fluid Model of Pulsatile Blood Flow through Porous Blood Vessels: A Comparative Study.

Research paper by Ashish A Tiwari, Satyendra S Singh Chauhan

Indexed on: 15 Jan '19Published on: 15 Jan '19Published in: Microvascular Research


Present work concerns the pulsatile blood flow of two-fluid model through porous blood vessels under the effect of radially varying viscosity. Blood is modeled as two-phase fluid model consisting a core region by non-Newtonian (Herschel-Bulkley) fluid and a plasma region modeled as Newtonian fluid. No slip condition has been used on wall and pressure gradient has been taken as periodic function of time. Up to first order approximate solutions of governing equations are obtained using perturbation approach. A comparative analysis for relative change in flow resistance between our model and previously studied single and two-fluid models without porous layer near wall has also been done. The wall of the blood vessel is composed by a thin Brinkman (porous) layer. The stress jump condition has been imposed on fluid-porous interface. Analytical expressions for the velocity profile, flow rate, wall shear stress and flow resistance have been obtained for different regions and the effect of plasma layer thickness, varying viscosity, yield stress, permeability and viscosity ratio parameter on the flow variables are pictorially discussed. It is perceived that values of flow rate for two-fluid model with porous region near wall is higher in comparison to two-fluid model without porous region near wall. Present study reveals a significant impact of glycocalyx layer on blood flow through blood vessels with a porous layer near wall. Copyright © 2019. Published by Elsevier Inc.