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Eastern equine encephalitis virus infection and hemophagocytic lymphohistiocytosis in a 5-month-old infant.

Research paper by Mary Y MY Mancao, Hamayun H Imran, Sharat S Chandra, Benjamin B Estrada, Maria M Figarola, Jeffrey J Sosnowski, Rosa R Vidal

Indexed on: 02 Jun '09Published on: 02 Jun '09Published in: The Pediatric infectious disease journal



Abstract

Eastern equine encephalitis virus infection is a rare sporadic central nervous system infection transmitted by a mosquito vector. Hemophagocytic lymphohistiocytosis (HLH) is a rare life-threatening disease associated with the inability of an overactive immune system to effectively respond to infections. Many viruses are known to trigger primary, as well as secondary, HLH. We report a pediatric case of eastern equine encephalitis virus-associated HLH which caused severe neurologic injury and death.

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