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Early investigations in drug delivery of onabotulinumtoxinA using combined fractional ablative laser with impact ultrasound versus injections of onabotulinumtoxinA for palmar hyperhidrosis: a right-left comparison trial.

Research paper by M C MC Issa, S P SP Torreão, M M Boechat, R R Luiz

Indexed on: 15 May '18Published on: 15 May '18Published in: British Journal of Dermatology



Abstract

SIR, we evaluated whether laser-assisted drug delivery (LADD) of onabotulinumtoxinA using combined fractional ablative laser with impact ultrasound was capable of reducing palmar sweat production. Palmar hyperhidrosis is a common disorder with substantial negative impact on quality of life. Palliative non-surgical treatments include antiperspirants, iontophoresis, oral anticholinergic drugs, and intradermal injection of botulinum toxin (BTX). Antiperspirants, although convenient, require repeated applications and cause skin irritations. Iontophoresis is effective in some cases, but it requires lengthy treatments. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.