Domino reactions with fluorinated five-membered heterocycles. alpha-Trifluoromethyl alpha-amino acids with unsaturated side-chains.

Research paper by K K Burger, L L Hennig, P P Tsouker, J J Spengler, F F Albericio, B B Koksch

Indexed on: 23 May '06Published on: 23 May '06Published in: Amino acids


Alpha-trifluoromethyl alpha-amino acids with unsaturated side-chains have been prepared from 5-fluoro-4-trifluoromethyloxazole and allyl, propargyl as well as terpene alcohols in a one-pot procedure.