DNA logic assembly powered by a triplex-helix molecular switch for extracellular pH imaging.

Research paper by Hongjie H Qi, Shuzhen S Yue, Sai S Bi, Caifeng C Ding, Weiling W Song

Indexed on: 14 Jul '18Published on: 14 Jul '18Published in: Chemical Communications


We demonstrate a strategy for pH-programmable self-assembly of DNA nanostructures by taking advantage of the pH dependence of reverse Hoogsteen interactions for a triplex-helix molecular switch. This strategy is successfully applied to the construction of molecular logic gates and imaging of extracellular pH.