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Distinctive subpopulations of the intestinal microbiota are present in women with unexplained chronic anovulation

Research paper by Hiroyuki Sasaki, Kazuhiro Kawamura, Toshihiro Kawamura, Toshitaka Odamaki, Noriko Katsumata, Jin-Zhong Xiao, Nao Suzuki, Mamoru Tanaka

Indexed on: 24 Dec '18Published on: 21 Dec '18Published in: Reproductive BioMedicine Online



Abstract

Do gut microbiota associate with the ovulatory cycle in women showing normogonadotropic anovulation' In humans, gut microbiota affect diverse physiological functions and dysbiosis (microbial imbalance) may lead to pathological syndromes. However, there is comparatively little information on the relevance of gut microbiota to reproductive functions in women. Here, we examined a group of women with idiopathic chronic anovulation, who do not exhibit any apparent endocrinological disorder with normogonadotropinemia, as they are suitable for investigating the relationship between intestinal bacteria and ovulatory disorders.