Diabetic syndrome in the Chinese hamster induced with monosodium glutamate

Research paper by K. Komeda, M. Yokote, Y. Oki

Indexed on: 01 Feb '80Published on: 01 Feb '80Published in: Cellular and Molecular Life Sciences


Neuronal necrosis in the arcuate and ventromedial hypothalamus regions is easily induced in 1-day-old Chinese hamsters by the administration of monosodium glutamate (MSG). New-born Chinese hamsters injected with MSG showed no sign of obesity, even when grown up, but apparently developed a diabetic syndrome.