Copper-catalyzed electrophilic amination using N-methoxyamines

Research paper by Yutaro Fukami, Takamasa Wada, Tatsuhiko Meguro, Noritaka Chida, Takaaki Sato

Indexed on: 09 Mar '16Published on: 29 Oct '15Published in: Organic & Biomolecular Chemistry


Copper-catalyzed electrophilic amination of a triarylboroxin using an N-methoxyamine to give quick access to a variety of anilines was reported. The reaction was especially useful for syntheses of functionalized anilines when combined with our previously reported nucleophilic addition to N-methoxyamides.

Graphical abstract 10.1039/C5OB02167G.gif