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Contribution of mobile genetic elements to Desulfovibrio vulgaris genome plasticity.

Research paper by Christopher B CB Walker, Sergey S Stolyar, Dylan D Chivian, Nicolas N Pinel, Jeffrey A JA Gabster, Paramvir S PS Dehal, Zhili Z He, Zamin Koo ZK Yang, Huei-Che B HC Yen, Jizhong J Zhou, Judy D JD Wall, Terry C TC Hazen, Adam P AP Arkin, David A DA Stahl

Indexed on: 10 Sep '09Published on: 10 Sep '09Published in: Environmental Microbiology



Abstract

The genome of Desulfovibrio vulgaris strain DePue, a sulfate-reducing Deltaproteobacterium isolated from heavy metal-impacted lake sediment, was completely sequenced and compared with the type strain D. vulgaris Hildenborough. The two genomes share a high degree of relatedness and synteny, but harbour distinct prophage and signatures of past phage encounters. In addition to a highly variable phage contribution, the genome of strain DePue contains a cluster of open-reading frames not found in strain Hildenborough coding for the production and export of a capsule exopolysaccharide, possibly of relevance to heavy metal resistance. Comparative whole-genome microarray analysis on four additional D. vulgaris strains established greater interstrain variation within regions associated with phage insertion and exopolysaccharide biosynthesis.