Comparative Proteomic Analysis of Bleomycin-induced Pulmonary Fibrosis Based on Isobaric Tag for Quantitation ☆ ☆☆

Research paper by Tiejun Yang, Yanlong Jia, Yongkang Ma, Liang Cao, Xiaobing Chen, Baoping Qiao

Indexed on: 19 Nov '16Published on: 18 Nov '16Published in: The American Journal of the Medical Sciences


Pulmonary fibrosis (PF) is a destructive pulmonary disease and the molecular mechanisms underlying PF is unclear. This study investigated differentially expressed proteins (DEPs) associated with the occurrence and development of PF in rat lung tissue with bleomycin-induced PF.