Quantcast

Clinical and microbiological features of a cystic fibrosis patient chronically colonized with Pandoraea sputorum identified by combining 16S rRNA sequencing and matrix-assisted laser desorption ionization-time of flight mass spectrometry.

Research paper by A A Fernández-Olmos, M I MI Morosini, A A Lamas, M M García-Castillo, L L García-García, R R Cantón, L L Máiz

Indexed on: 16 Dec '11Published on: 16 Dec '11Published in: Journal of clinical microbiology



Abstract

Clonal isolates identified as various nonfermentative Gram-negative bacilli over a 5-year period from sputum cultures of a 30-year-old cystic fibrosis patient were successfully reidentified as Pandoraea sputorum by combining 16S rRNA sequencing and matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS). Decreased lung function improved after 1 year of azithromycin and inhaled 7%-hypertonic saline treatment.