Chronic meningoencephalitis with mixed pathology mimics progressive supranuclear palsy.

Research paper by Marian L ML Dale, Deniz D Erten-Lyons, Frank F Bittner, Randy R Woltjer

Indexed on: 21 Dec '18Published on: 21 Dec '18Published in: BMJ case reports


We report a case of a progressive supranuclear palsy-like phenotype with rapidly progressive dementia and prominent language and executive dysfunction. Pathological examination revealed no midbrain or white matter tauopathy, but rather chronic meningoencephalitis and other mixed pathology. The cerebrospinal fluid (CSF) in this case showed a novel antibody against central nervous system and renal tissue. © BMJ Publishing Group Limited 2018. No commercial re-use. See rights and permissions. Published by BMJ.