Chronic infection, inflammation, and epithelial ovarian cancer.

Research paper by J T JT Quirk, J M JM Kupinski

Indexed on: 17 Oct '01Published on: 17 Oct '01Published in: Medical Hypotheses


At the present time, the etiology of epithelial ovarian cancer is poorly understood. It has recently been recognized that certain chronic infectious agents may contribute to carcinogenesis by inducing a state of persistent inflammation. Since the female upper genital tract is a frequent site of chronic infections, we propose various strategies that may be useful for determining the potential role of chronic infection and persistent inflammation in the pathogenesis of epithelial ovarian cancer.