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Cancer-Specific Splicing Changes and the Potential for Splicing-Derived Neoantigens.

Research paper by Luisa Escobar LE Hoyos, Omar O Abdel-Wahab

Indexed on: 15 Aug '18Published on: 15 Aug '18Published in: Cancer Cell



Abstract

In this issue of Cancer Cell, Kahles et al. perform a comprehensive analysis of RNA splicing across cancer types and identify novel correlations between genetic alterations and splicing in cancer. In addition, they identify that tumor-specific splicing has the potential to generate a large new class of tumor-specific neoantigens. Copyright © 2018 Elsevier Inc. All rights reserved.

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