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BRAF V600E Mutation as a Negative Prognostic Determinant in Resected Colorectal Liver Metastases

Research paper by Moretto R, Cremolini C, Falcone A.

Indexed on: 23 Dec '18Published on: 01 Dec '18Published in: JAMA surgery



Abstract

To the Editor In their article, Margonis et al report the role of BRAF V600E mutation as the strongest determinant of prognosis in a large cohort of 849 patients with resected colorectal liver metastases (CRLM). Their findings are consistent with previous reports in the literature, including our retrospective series.