Biometrical genetic analysis of the cotwin control design

Research paper by David L. Duffy

Indexed on: 01 Jul '94Published on: 01 Jul '94Published in: Behavior Genetics


The twin-cotwin matched case-control design can be interpreted in terms of bivariate genetic factor models. I derive expressions for the expected intrapair difference for a trait correlated with the variable on which discordance was selected.