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Bioactive Pimarane-type Diterpenes from Marine Organisms.

Research paper by Xiaoli X Wang, Haobing H Yu, Yixin Y Zhang, Xiaoling X Lu, Bin B Wang, Xiaoyu X Liu

Indexed on: 25 Jul '17Published on: 25 Jul '17Published in: Chemistry & Biodiversity



Abstract

Marine organisms represent an abundant sources of bioactive natural products with unique chemical structure. Pimarane diterpenes are a structurally diverse family of natural products with various biological activities and pharmacological properties. A prolific source of new marine-derived pimarane diterpenes have attracted considerable interest because of their unique structural diversity and varied biological activities, including antimicrobial, antitumor, and antiproliferative activities. This review provides a comprehensive overview of the structures, names, bioactivities, and references of 80 marine-derived pimarane-type natural products for the first time. This article is protected by copyright. All rights reserved.