Bilateral pleural effusion with APLA positivity in a case of rhupus syndrome.

Research paper by Kaushik K Saha, Arnab A Saha, Mrinmoy M Mitra, Prabodh P Panchadhyayee

Indexed on: 08 Nov '14Published on: 08 Nov '14Published in: Lung India : official organ of Indian Chest Society


Rhupus syndrome is a rare syndrome characterized by overlap of rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). Our patient was a diagnosed case of RA and developed SLE 2 years after. She was a middle-aged woman, presented with bilateral pleural effusion with exacerbation of skin and joint symptoms of SLE. We diagnosed the case as tubercular pleural effusion by positive Mycobacterium tuberculosis in bactec 460 culture. She had also anti-phospholipid antibody positivity without any symptoms and signs of thrombosis.