Behavioural changes in the rat following infection with varicella-zoster virus.

Research paper by S M SM Fleetwood-Walker, J P JP Quinn, C C Wallace, G G Blackburn-Munro, B G BG Kelly, C E CE Fiskerstrand, A A AA Nash, R G RG Dalziel

Indexed on: 29 Sep '99Published on: 29 Sep '99Published in: The Journal of general virology


Following the establishment of a chronic varicella-zoster virus infection in the rat, behavioural allodynia and hyperalgesia were observed in the injected, but not the contralateral hind limb up to 33 days post-infection. This model may prove useful in investigating mechanisms involved in the establishment of post-herpetic neuralgia.