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Behavioral Effects of Potentiated Antibodies to Morphine and μ-Opioid Receptors during Withdrawal Syndrome

Research paper by I. F. Pavlov, O. I. Epstein, M. B. Shtark

Indexed on: 01 Jan '03Published on: 01 Jan '03Published in: Bulletin of Experimental Biology and Medicine



Abstract

We studied the effects of potentiated antibodies to morphine and μ-opioid receptors on animal behavior in the forced swimming test and reaction of light avoidance after morphine withdrawal. Antibodies to morphine normalized behavioral characteristics in the forced swimming test, while antibodies to μ-opioid receptors reduced dark preference in animals.