Association Between Hidradenitis Suppurativa and Metabolic Syndrome.

Research paper by M J M MJM Rodríguez-Zuñiga, H A HA García-Perdomo, A G AG Ortega-Loayza

Indexed on: 10 Mar '19Published on: 09 Mar '19Published in: Actas Dermo-Sifiliográficas (English Edition)


Recent studies have shown a relationship between hidradenitis suppurativa (HS) and metabolic syndrome (MS), but no meta-analysis has been restricted to studies that have been adjusted for confounders. To determine the association between HS and MS. A systematic review and meta-analysis of observational studies on HS and MS in adults were performed from MEDLINE, SCOPUS, SCIELO, GOOGLE SCHOLAR, SCIENCE DIRECT and LILACS from the inception of the databases to January 2016. We performed a random effects model meta-analysis for those studies reporting adjusted and crude ORs with 95% confidence intervals (CI). The subgroup analysis was related to the type of HS population (general HS population vs. hospital HS population) and age group (adults vs. children and adults). Five studies, including 3950 HS patients, were analyzed. We found that MS was present in 9.64% of HS patients (OR 1.82, 95% CI 1.39-2.25). Studies from a tertiary care center dermatology clinic hospital (OR 2.82, 95% CI 0.58-5.06) reported a greater risk for MS than studies carried out in the general population (OR 1.78, 95% CI 1.34-2.22). Studies that included pediatric population reported a significant association (OR 2.10, 95% CI 1.58-2.62). There were few adjusted studies. HS patients have an increased risk for MS. Clinicians should consider screening HS patients for metabolic risk factors. Copyright © 2019 AEDV. All rights reserved.