An automated workflow for the anatomo-functional mapping of the barrel cortex

Research paper by Lorraine Perronnet, María Eugenia Vilarchao, Guillaume Hucher, Daniel E. Shulz, Gabriel Peyré, Isabelle Ferezou

Indexed on: 14 Mar '16Published on: 15 Sep '15Published in: Journal of Neuroscience Methods


The rodent barrel cortex is a widely used model to study the cortical processing of tactile sensory information. It is notable by the cytoarchitecture of its layer IV, which contains distinguishable structural units called barrels that can be considered as anatomical landmarks of the functional columnar organization of the cerebral cortex. To study sensory integration in the barrel cortex it is therefore essential to map recorded functional data onto the underlying barrel topography, which can be reconstructed from the post hoc alignment of tangential brain slices stained for cytochrome oxidase.

Figure 10.1016/j.jneumeth.2015.09.008.0.jpg
Figure 10.1016/j.jneumeth.2015.09.008.1.jpg
Figure 10.1016/j.jneumeth.2015.09.008.2.jpg
Figure 10.1016/j.jneumeth.2015.09.008.3.jpg
Figure 10.1016/j.jneumeth.2015.09.008.4.jpg