An assessment of R&D productivity in the pharmaceutical industry.

Research paper by Nicola N Dimitri

Indexed on: 28 Oct '11Published on: 28 Oct '11Published in: Trends in Pharmacological Sciences


Recent reports suggest that R&D productivity in the pharmaceutical industry can be strengthened by reducing costs both in the early phase and, mostly, in the clinical phase of drug discovery. However, a cost-benefit probabilistic analysis reveals that despite high costs, the clinical phase shows healthy productivity, whereas the early phase, particularly lead optimization, exhibits very low productivity.