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Alkyl and 2-hydroxy derivatives of imidazo]4,5-b]pyrazine and their N-oxides

Research paper by A. S. Elina, I. S. Musatova

Indexed on: 01 May '74Published on: 01 May '74Published in: Chemistry of Heterocyclic Compounds



Abstract

N-Monoxides and N,N-dioxides of some alkyl and hydroxy derivatives of imidazo[4,5-b]pyrazine were synthesized. It was proved that the nitrogen atoms of the pyrazine ring are oxidized; alkylation of N1 sterically hinders oxidation of N7. The hydrolytic cleavage of imidazo[4,5-b]pyrazines and their N-oxides was studied.