Age-related infertility.

Research paper by Natalie M NM Crawford, Anne Z AZ Steiner

Indexed on: 16 Feb '15Published on: 16 Feb '15Published in: Obstetrics and Gynecology Clinics of North America


Oocyte number and quality decrease with advancing age. Thus, fecundity decreases as age increases, with a more rapid decline after the mid-30s. Patients more than 35 years old should receive prompt evaluation for causes of infertility after no more than 6 months of attempted conception. Patients with abnormal tests of ovarian reserve have a poorer prognosis and may need more expedited and aggressive treatment. Although oocyte donation is the best method to overcome age-related infertility, other treatment options may help women proceed quicker toward pregnancy. Patients at an advanced age should be counseled and evaluated before undergoing infertility treatments.

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